We study how biological cells respond to and generate mechanical forces, with a focus on platelets and blood clotting. Active projects are in three key areas:
- Enhancing technology and methods in cellular biomechanics, including enhancing the resolution, translatability, reliability, and biological mimicry of methodologies.
- Understanding how cells fundamentally respond to and generate forces, including understanding factors that drive platelet force generation and sex and hormone effects on platelet mechanical activation and function.
- Translating cellular biomechanics methods and knowledge toward the betterment of human health.